Low dose naltrexone
Oral capsule$35/mo*
Low-dose naltrexone (LDN) uses very low doses of naltrexone to prompt the body to raise its own endorphins and may help calm neuroinflammation.
- Acts on immune cells tied to neuroinflammation
- May support a healthy inflammatory response
- Uses a small fraction of the standard naltrexone dose
*Billed every 3 months, paid upfront.
Includes provider review · Ships in 3–5 days if prescribed
- Licensed providers
- Free shipping
- US-based pharmacies
Naltrexone is FDA-approved for opioid and alcohol use disorder. Naltrexone is not FDA approved for treatment related to inflammatory response treatment. Low dose naltrexone is a compounded product and is not FDA reviewed or approved for safety, effectiveness, or quality. This product is prescribed only if a licensed health care provider determines it is clinically appropriate following evaluation. Individual results vary. Elysium Health is not a clinical provider but contracts with third-party clinical entities with licensed health care providers which provide medical care to individuals that use the Elysium Health platform. Image for illustration only. Actual product may vary.
Why LDN
Low doses, a different effect
At very low doses, naltrexone briefly blocks opioid receptors, which prompts the body to raise its own endorphins. It also acts on glial cells (TLR4) in the nervous system, which may help calm neuroinflammation.
LDN is used off-label and is compounded; evidence is limited and emerging, drawn from small trials and clinical experience. Standard-dose naltrexone is FDA-approved for opioid and alcohol use disorder — not for the uses described here.
How LDN works
What it does in the body
LDN works differently at low doses than standard naltrexone does at full dose.
May support endorphin production
At very low doses, naltrexone briefly blocks opioid receptors, prompting the body to raise its own endorphins.
Supports healthy inflammation
It acts on glial cells (TLR4) in the nervous system, which may help calm neuroinflammation.
Low-dose, not standard-dose
LDN uses far lower doses than standard naltrexone, for a different effect—an investigational, off-label use.
Our medical team
Developed with expert clinicians
From our Chief Medical Officer
The goal of longevity treatment is not simply more years. It is more good years. We built TELI to bring clinical rigor to a space that has too often lacked it, so people can pursue their healthspan with the same confidence they bring to the rest of their medical care.
How The Elysium Longevity Institute works
From intake to your doorstep
- Step 1
Complete your medical intake
Choose your protocol, then share your health history and goals to begin your longevity care.
What your provider needs
- Step 2
Provider review
A licensed provider will review your intake and prescribe a personalized protocol, if appropriate.
Licensed & confidential
- Step 3
Shipped to your door
If prescribed, a licensed partner pharmacy will ship to your door free of charge within 3–5 business days.
Fast, free shipping
- Step 4
Ongoing care
Message your provider any time through your TELI portal.
On-demand support
FAQ
Frequently asked questions
What is low-dose naltrexone?
LDN uses very low doses of naltrexone—far below the standard dose—to prompt the body to raise its own endorphins and to act on glial cells tied to neuroinflammation.
How do you take low-dose naltrexone?
LDN is an oral capsule taken once daily. If prescribed, your provider gives you exact instructions for your prescription.
What are the side effects of low-dose naltrexone?
Side effects may include vivid dreams, trouble sleeping, headache, nausea. Your provider reviews your health history and stays available throughout your treatment.
Who shouldn’t take low-dose naltrexone?
Do not take LDN if you use opioids of any kind, including tramadol, buprenorphine, or opioid cough medicines, or have used them in the past 7 to 10 days. LDN blocks opioid pain relief, so tell any surgeon, dentist, or emergency provider that you take it. Tell your provider about every medication you take, and let them know if you are pregnant, breastfeeding, or trying to become pregnant. If you take thyroid medication, your provider may want to monitor your thyroid levels more closely when you start LDN.
References
LDN is used off-label and is compounded; evidence is limited and emerging, drawn from small trials and clinical experience. Standard-dose naltrexone is FDA-approved for opioid and alcohol use disorder — not for the uses here.
- McKenzie A, Bittar T, Dombrower R, Raman D, Hussain H, Theeraphapphong N, McKenzie SM, Abd-Elsayed A. Low-Dose Naltrexone in Chronic Pain Management: Mechanisms, Evidence, and Clinical Implications. J Pers Med. 2026 Mar 6;16(3):151. doi: 10.3390/jpm16030151. PMID: 41893019; PMCID: PMC13027662.
Ready to start Low dose naltrexone?
Complete your intake online. A licensed provider will review your information and, if eligible, prescribe a personalized plan.
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